Lipogenesis in Human Adipose Tissue: Some Effects of Nibbling and Gorging

Lipogenesis in human adipose tissue: some effects of nibbling and gorging.

Six grossly obese patients were fed 5000 calorie diets for 4 wk. During one period of 2 wk, the calories were consumed over 4 hr (gorging) and during the other 2 wk, the dietary intake was spread over 20 hr (nibbling). Each of these periods followed a low caloric intake which lasted at least 10 days. Three male patients (group I) were studied at or near their maximal weight and three females (g...

Lipogenic activation after nibbling and gorging in mice.

Lipogenic activation was studied in mice that had been restricted to a single large meal once a day rather than being allowed to eat at frequent intervals throughout the night. Mice were injected intravenously with [U-(14)C]glucose, and the flux of glucose C to total lipid fatty acids (TLFA) and to all "end products" was estimated from serial plasma glucose specific activities and measurements ...

Lipogenesis in ovine adipose tissue in tissue culture.

Insulin and rosiglitazone regulation of lipolysis and lipogenesis in human adipose tissue in vitro.

Lipolysis is an important process determining fuel metabolism, and insulin regulates this process in adipose tissue. The aim of this study was to investigate the long-term effects of insulin, an insulin enhancer (rosiglitazone [RSG]), and insulin in combination with RSG on the regulation of lipolysis and lipogenesis in human abdominal subcutaneous fat. Lipolysis and lipogenesis were assessed by...

Lipogenesis in brown adipose tissue and its regulation.

acids and ketone bodies in the circulation, and there is a need to conserve glucose because of the relatively low carbohydrate content of the milk (for review see Williamson, 1985). During this period of development, brown adipose tissue has a vital role in thermogenesis, and the level of GDP-binding to brown-fat mitochondria is considerably increased (Sundin & Cannon, 1980). The weight of inte...